Common risks of cloning
Cloning an animal with somatic cell nuclear transfer is very inefficient. The success rate of cloning ranges from 0.1% to 3%,with that said, for every 1000 tries at cloning, only one to 30 clones are made. That's a lot of effort with little to no benefit
Why is this? Here are some reasons:
- The nucleated egg and the transferred nucleus may not be compatible
- An egg with a newly transferred nucleus may not begin to divide or develop properly
- Implantation of the embryo into the surrogate mother might fail
- The pregnancy itself might fail
The Cloned animals do survive they are usually much larger than the normal host. this is called "Large Offspring Syndrome" (LOS). Clones with LOS have abnormally large organs. This can lead to breathing, blood flow and other problems.
LOS doesn't always occur, so scientists cannot predict whether it will happen in any given clone. Also, some clones without LOS have developed kidney or brain malformations and impaired immune systems, which can cause problems later in life.